Lab Members | The Kwon Lab

Current Lab Members

Doug Kwon

Principal Investigator - dkwon@mgh.harvard.edu

Doug is a physician scientist at the Ragon Institute of MGH, MIT and Harvard and Director of Clinical Operations at the Ragon Institute. He has a clinical practice in the division of Infectious Diseases at Massachusetts General Hospital. He received his M.D. Ph.D. degrees from New York University and then underwent Internal Medicine training at the University of California, San Francisco and New York Hospital/Weill Cornell Medical Center. He then completed his training in the combined Massachusetts General Hospital and Brigham and Women’s Hospital Infectious Disease fellowship program.

Seth Bloom

Postdoctoral Fellow - smbloom@mgh.harvard.edu

Seth joined the Kwon Lab in July 2016. He is an Infectious Diseases fellow in the combined Massachusetts General Hospital and Brigham & Women’s Hospital program. He earned a BA in Biology from Washington University in St. Louis, Missouri, in 2004, performing his undergraduate thesis work on influenza virus. Seth stayed at Washington University for his MD/PhD training and Internal Medicine residency, focusing his research on the role of commensal intestinal bacteria in a mouse model of inflammatory bowel disease. In the Kwon lab, his current work involves understanding interactions between bacterial microbiota and mucosal lymphocytes in the female genital tract, with a focus on how these interactions may influence risk of primary HIV infection. Outside of the lab, Seth enjoys running, hiking, spending time with family, and international travel.

Upasana Das Adhikari

Postdoctoral Fellow - udasadhikari@mgh.harvard.edu

Upasana joined the Kwon Lab as a postdoctoral fellow in December 2018. Before moving to Boston, she was a Signgene Fellow doing her Ph.D. in a collaborative project between the Hebrew University of Jerusalem and Max Delbruck Centre of Molecular Medicine in Berlin. During her Ph.D., she studied the gut epithelial stem cell regeneration addressing the crosstalk between reserve and active stem cells. This led her to become fascinated by the three amigos of the gut: the epithelium, Gut Associated Lymphoid Tissue, and the microbiome. In the Kwon Lab, Upasana will study the cause of the misbalance of these interactions during HIV progression to halt the viral replication in the gut reservoir. In her free time, she loves to dance salsa and bachata!

Fatima Hussain

Postdoctoral Fellow - fhussain3@mgh.harvard.edu

Fatima joined the Kwon Lab as a Research Fellow in May 2020 to study the female genital tract microbiome from an evolutionary ecology perspective. For her PhD, she studied bacteriophage-driven evolution of marine microbes with Martin Polz at MIT. Her previous work focused on near-term resistance evolution to lytic phages in bacteria of the genus Vibrio, and the role of lysogenic phages in shaping Vibrio genomic diversity. She applies the same framework in her postdoctoral work to determine how ecological interactions, both phage-bacteria and bacteria-bacteria, drive the intra-species evolutionary dynamics of Lactobacillus populations in the vagina. Ultimately, she aims to use her research to design ecologically-informed microbial therapeutics for women’s health. Prior to becoming a microbiologist, Fatima studied Environmental Engineering and Women’s and Gender Studies at MIT and Stanford. In her free time, she enjoys hosting dinner parties, culturing sourdough, yoga, and gardening.

Joshua Gammon

Postdoctoral Fellow - jgammon1@mgh.harvard.edu

Josh joined the Kwon Lab as a postdoctoral fellow in July 2020. He completed his Ph.D. in bioengineering at the University of Maryland, where he was a PhRMA Foundation graduate fellow in Christopher Jewell’s lab. His doctoral research involved leveraging biomaterials to locally target immunotherapies to lymph nodes to promote immunological tolerance. In the Kwon Lab, Josh’s work focuses on studying the interactions between microbes in the female genital tract and local inflammation. He aims to use his research to inform the design of interventions to prevent HIV infection. In his spare time, he enjoys reading, fishkeeping, sampling tasty beers, and hiking.

Benjamin Read

Postdoctoral Fellow - bread1@mgh.harvard.edu

Ben joined the Kwon lab as a postdoctoral fellow in July 2021. He completed his Ph.D. in medical engineering at MIT, where his research focused on engineering nanoparticle antigens to enable innate immune recognition and directed accumulation within draining lymph nodes to improve immune responses. In the Kwon Lab, Ben works to elucidate the immunological changes that occur in the female genital tract following HIV infection and how these changes evolve over time. He aims to utilize his research to inform the development of the next generation of interventions to prevent and treat HIV infection. In his free time, Ben enjoys running, reading, and playing board games with friends.

Jiawu Xu

Lab Manager - jxu25@mgh.harvard.edu

Jiawu had the honor of joining the Kwon Lab in May 2018. He is a research scientist working on microbes in the gut and female genital tract, and their interactions with HIV/AIDS. As the lab manager, he enjoys helping the lab run smoothly and efficiently and providing support and encouragement to the hard-working Kwonnies each day. Prior to joining the Kwon Lab, Jiawu conducted research on population genetics, molecular ecology and evolution at Brigham Young University and Rutgers University, and on human microbiome and metagenomics at The University of Oklahoma. Jiawu received his PhD in biology from The Chinese University of Hong Kong, with a major in genetics and molecular evolution. He likes to do research in genetics, genomics and microbiome in relation to human health and diseases.

Joseph Elsherbini

Data Scientist/Bioinformatician - jelsherbini@mgh.harvard.edu

Joseph joined the Kwon Lab in 2021 as the Bioinformatician and Data Scientist for the lab. He did his PhD in the MIT Microbiology program working in Martin Polz’s lab on the temporal dynamics of closely related microbes from the coastal ocean. In the Kwon Lab he is working on making existing datasets in the lab easier for everyone to use and creating pipelines to do common tasks in the lab in a reproducible way. When he’s not supporting research projects in the lab, he is usually making coffee, watering his plants, or scouring the internet for new guitar pedals.

Meilin Zhu

Graduate Student - mzhu@broadinstitute.org

Meilin Zhu is a PhD candidate and NSF GRFP fellow at MIT in Biological Engineering, co-advised with Dr. Paul Blainey. She completed her bachelor’s degree in Biochemistry at Arizona State University, where she developed point-of-care diagnostic tools for HPV-associated cervical cancer screening in low resource settings. In graduate school, Meilin decided to explore the world of microbes, with projects including, 1) developing high throughput screening methods for discovering new antibiotic potentiators against gram negative ESKAPE pathogens, and 2) understanding how bacterial metabolism in the female genital tract can be leveraged to rationally design and shift microbiota compositions. In her free time, Meilin can be found at the park chasing after her crazy corgi or trying out new restaurants on Newbury St.

Blythe Gulley

Project Manager - bbgulley@mgh.harvard.edu

Blythe Gulley joined the Kwon Lab as Staff Assistant in July 2020. She received her B.A. in English & Comparative Literature from UNC-Chapel Hill, where she was involved with The Carolina Quarterly and the UNC Institute of Politics. In 2018, she co-curated an exhibition for her research seminar: “Reconstructing Frankenstein’s Monster: Mary Shelley’s World in Print.” When she’s not at the lab, Blythe can be found wandering around museums, reading a good book, or cheering on UNC’s basketball team!

Tess Brunner

Research Technician - tbrunner@mgh.harvard.edu

Tess Brunner joined the Kwon Lab as a Research Technician in June 2021.

Suzanne Carpe Elías

Research Technician - SCarpeElias@mgh.harvard.edu

Suzanne had the honor of joining the Kwon Lab as a Research Technician in July 2022 to support the work of postdoctoral fellows Ben Read and Josh Gammon. Born and raised in El Salvador, she firsthand experienced the devastating effects of infectious diseases at a young age. Suzanne received a B.S. in Biology and French from Trinity College, where she researched the role of the caudal gene in Tribolium castaneum development. She also studied the long-term effects of COVID-19 at Saint Francis Hospital and examined an anti-IL-1β and anti-PD1 immunotherapy for metastatic pancreatic cancer at Dana-Farber Cancer Institute. These experiences led her to become fascinated by infectious diseases and immunology. When she is not in lab, she can be found reading, running around Boston, or traveling the world!

Aditi Kannan

Research Technician - akannan5@mgh.harvard.edu

Aditi joined the Kwon Lab as a Research Technician in July 2022. She received her B.A. from Wellesley College where she majored in Biochemistry and minored in Music. While at Wellesley, her research focused mainly on microbial ecology and human gut microbiology. In the Kwon Lab, she aims to study the vaginal microbiome and microbe-host interactions within the vagina under the mentorship of Dr. Fatima Hussain and Dr. Upasana Das Adhikari. Outside of the lab, Aditi can be found playing the violin or listening to music, walking around the city, or reading a novel!

Kwon Lab – South Africa

Sinaye Ngcapu

Postdoctoral Fellow - sinaye.ngcapu@caprisa.org

Dr Sinaye Ngcapu, is a postdoctoral fellow under the mentorship of Drs Douglas Kwon, JoAnn Passmore and Quarraisha Abdool Karim at CAPRISA Mucosal Immunology Laboratory, Durban, South Africa. He is also an honorary lecturer at the Nelson R Mandela School of Medicine, University of KwaZulu-Natal, South Africa. Sinaye’s main research focuses are on characterizing the earliest immune responses and the potential mucosal risk factors involved in susceptibility and protection to HIV infection in the genital mucosa. In collaboration with Dr Kwon, Sinaye aims to understand the composition of bacterial species in young women of different ethnic groups in South Africa and characterize the connection between vaginal microbiome, endogenous reproductive hormones, genital inflammation and risk of HIV acquisition. In his spare time, he spends time with family, watch movies and he is the best couch coach ever produced by science.

Nondumiso Xulu

Research Technician - nxulu@mgh.harvard.edu

Nondumiso is in the South African branch of the Kwon Lab and HIV Pathogenesis Programme (HPP) which she joined in October 2016. She has always been passionate about science, and after her Matric she enrolled for BSc. Microbiology (University of Zululand, Kwa-Dlangezwa, South Africa). After completion of her undergraduate degree, she went on to enroll for postgraduate studies with a Bachelor of Medical Science Honours and Master Of Medical Science (University of Kwa-Zulu Natal, Durban, South Africa). Her research projects focused on the characterization Chlamydia trachomatis inclusions as well as the identification and characterization of a novel toxin produced by some serovars of Chlamydia trachomatis. In the Kwon Lab, Nondumiso focuses on processing cytobrush and PBMC samples, flow cytometry and cell sorting. For fun, she enjoys dancing and watching football (soccer).

Suuba Demby

Undergraduate Researcher - suubademby@college.harvard.edu

Suuba joined the Kwon Lab in October of 2020. She is currently studying Molecular and Cellular Biology at Harvard College, with a minor in Energy and Environment. Prior to joining the lab, Suuba spent five years living overseas in Malawi and has worked on public health and policy-based projects in Sierra Leone for the past two years. In the Kwon Lab, Suuba is studying the female genital tract microbiome from an evolutionary ecology perspective under the mentorship of Dr. Fatima Hussain. Outside of the lab, Suuba enjoys photography, biking, and working as an EMT.

Honorary Lab Members:

Boomer

Honorary Kwon Lab Member - boomer@kwonlab.org

Boomer joined the Kwon Lab in the fall of 2014. He has advanced degrees in squirrel chasing and table scrap eating. Although technically banned from the bench, he continues to assist with computational projects and advises graduate students on how to successfully deal with the stresses of completing a Ph.D.