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Open Positions:
Postdoctoral Research Fellow - Mucosal Immunology & the Microbiome

Direct Supervisor:  Douglas S. Kwon, MD PhD, Assistant Professor in Medicine
Email: dkwon@mgh.harvard.edu
Phone: (857) 268-7009
Employing Hospital and Department: Ragon Institute of MGH, MIT, and Harvard
Minimum degree and field of knowledge:  PhD and/or MD with experience in immunology
Years experience required:  At least 3 years of doctoral research experience

Summary:
The Kwon Laboratory (www.kwonlab.org) at the Ragon Institute of MGH, MIT and Harvard at the Massachusetts General Hospital in Boston has an opening for a highly motivated postdoctoral fellow to study alterations in the microbiome that occur with HIV infection, following up on recent studies published by our group in ImmunityThe Lancet Infectious Diseases, and Cell Host and Microbe (see further details here).  This includes examination of the role of the microbiome in the female genital tract and gut and the impact of these changes on host mucosal immunity. The person hired will work under the supervision of Dr. Kwon conducting patient-oriented translational research involving transcriptional and immunologic profiling of mucosal immune populations and the microbiome with the aim of generating new approaches to treat and prevent HIV infection using samples from well-characterized cohorts in the U.S. and sub-Saharan Africa. The position will also involve the use of novel in vivo model system, such as germ-free and humanized mice.

Candidates will have ample opportunities to acquire and develop new skills, work closely with the PI and collaborators, and communicate results to the scientific community through conference presentations and peer-reviewed publications while working in a supportive, highly collaborative, and energetic environment.  State-of-the-art facilities are available within an exceptional research setting.

Job Duties:
Under the direction of the principal investigator, the applicant will independently carry out activities performing laboratory research. Duties include:

  • Guide research projects through experimental design, conduct experiments, and analysis of data
  • Maintain detailed documentation of the experimental work
  • Present data within and outside of the laboratory group at meetings and symposia
  • Work closely within the group and with outside collaborators
  • Mentor students and technicians
  • Maintain close communications with the PI regarding progress
  • Write, edit, and submit manuscripts/abstracts detailing the results of the project
  • Demonstrate integrity, excellence, accountability and teamwork in all interactions

Qualifications:

  • A Ph.D. and/or M.D. with relevant experience in immunology, murine models, and/or transcriptional profiling preferred
  • Experience with flow cytometry, cell culture
  • Prior work with murine models preferred
  • Highly motivated and independent, with the ability to work in a dynamic team environment
  • Exceptional organizational skills and excellent attention to detail
  • Strong oral and written communications skills
  • Must have good interpersonal skills
  • Occasional weekend or evening flexibility

Application information: The position is open immediately although the start date is flexible. Please submit a cover letter, CV, and references to Dr. Doug Kwon at dkwon@mgh.harvard.edu. Unfortunately, due to the number of applications we receive, we may not be able to reply individually to all inquiries.  All applicants, including those from abroad, must be able to come to Cambridge, MA USA for an in-person interview.

Postdoctoral Research Fellow - Murine Models of Mucosal Immunology

Direct Supervisor:  Doug S. Kwon, MD PhD, Associate Professor in Medicine
Email: dkwon@mgh.harvard.edu
Phone: (857) 268-7009
Website: www.kwonlab.org

Employing Hospital and Department: Ragon Institute of MGH, MIT, and Harvard
Minimum degree and field of knowledge: PhD and/or MD with experience in immunology, microbiology and/or computational approaches
Years experience required: At least 3 years of doctoral research experience

Summary:
The Kwon Laboratory (www.kwonlab.org) at the Ragon Institute of MGH, MIT and Harvard at the Massachusetts General Hospital in Boston has an opening for a highly motivated postdoctoral fellow to study mechanistic links between the vaginal microbiome and adverse reproductive outcomes, following up on recent studies published by our group in Immunity, The Lancet Infectious Diseases, and Cell Host and Microbe (see further details here).  This includes examination of the role of the vaginal microbiome that impact host mucosal immunity and HIV acquisition risk. The person hired will work under the supervision of Dr. Kwon conducting patient-oriented translational research using samples from well characterized cohorts in the U.S. and sub-Saharan Africa involving transcriptional and immunologic profiling of mucosal immune populations and the microbiome using novel technologies, with the aim of generating new approaches to treat and prevent HIV infections. This includes the use of novel murine models to perform mechanistic studies of the role of mucosal immunity in the female genital tract on HIV susceptibility.

Candidates will have ample opportunities to acquire and develop new skills, work closely with the PI and collaborators, and communicate results to the scientific community through conference presentations and peer-reviewed publications while working in a supportive, highly collaborative, and energetic environment.  State-of-the-art facilities are available within an exceptional research setting.

Job Duties: Under the direction of the principal investigator, the applicant will independently carry out activities performing laboratory research. Duties include:

  • Guide research projects through experimental design, conduct of experiments, and analysis of data
  • Maintain detailed documentation of the experimental work
  • Present data within and outside of the laboratory group at meetings and symposia
  • Work closely within the group and with outside collaborators
  • Mentor students and technicians
  • Maintain close communications with the PI regarding progress
  • Write, edit, and submit manuscripts/abstracts detailing the results of the project
  • Demonstrate integrity, excellence, accountability and teamwork in all interactions

Ideal Qualifications:

  • A Ph.D. and/or M.D. with relevant experience in immunology and mouse work preferred
  • Experience with flow cytometry, cell culture
  • Highly motivated and independent, with the ability to work in a dynamic team environment
  • Exceptional organizational skills and excellent attention to detail
  • Strong oral and written communications skills
  • Must have good interpersonal skills
  • Prior work with murine models

Application information: The position is open immediately although the start date is flexible. Please submit a cover letter, CV, and references to Dr. Doug Kwon at dkwon@mgh.harvard.edu. Unfortunately, due to the number of applications we receive, we may not be able to reply individually to all inquiries. All applicants, including those from abroad, must be able to come to Cambridge, MA USA for an in-person interview.

Research Technologist

Direct Supervisor:  Doug S. Kwon, MD PhD, Associate Professor in Medicine
Email: dkwon@mgh.harvard.edu
Phone: (857) 268-7009
Website: www.kwonlab.org

Employing Hospital and Department: Ragon Institute of MGH, MIT, and Harvard
Minimum degree and field of knowledge: Bachelor’s degree required, Master’s degree preferred
Years experience required: 4+ years work in a scientific laboratory required

Summary:

The Kwon Laboratory at the Ragon Institute of MGH, MIT, and Harvard at the Massachusetts General Hospital in Boston (www.kwonlab.org) has an opening for a highly motivated Research Technologist to study the immunopathogenesis of HIV infection and the human microbiome at mucosal tissue sites, including the female reproductive tract. The overall goal is to conduct human translational research to help reduce the spread of HIV, particularly among young women in sub-Saharan Africa. The person hired will work under the supervision of Dr. Kwon conducting patient-oriented translational research involving cutting-edge technologies. The position will involve handling and processing of tissue and blood samples, performance of anaerobic bacteriology, immunologic assays, nucleic acid extractions, PCR, next-generation sequencing, and utilizing novel assays to study mucosal immune responses to HIV and mucosal bacteria. The position will also involve general lab organization and assistance with lab logistics.

This is a great opportunity for someone interested in pursuing a career in scientific research or medicine while working in a supportive, highly collaborative, and energetic environment. The lab studies samples from ongoing clinical cohorts based in the US and South Africa examining the risk of HIV, HIV pathogenesis, and other adverse reproductive outcomes. State-of-the-art facilities are available within an exceptionally energetic research setting.

The Kwon lab is committed to providing a diverse, inclusive, and supportive environment; appropriately qualified applicants from all backgrounds will be considered.

Job Duties: Under the direction of the principal investigator, the applicant will independently carry out activities performing laboratory research. Duties include:

  • Perform experiments analyzing microbial and tissue samples from human subjects, assessing the impact of the HIV infection and microbiome on health
  • Perform and assist with experiments involving bacteriology, immunologic assays, microscopy, flow cytometry and molecular biology
  • Analyze data and present findings to others
  • Maintain detailed documentation of the experimental work
  • Ensure quality control of equipment, reagents and cellular components
  • Work closely within the group and with outside collaborators
  • Maintain close communications with PI regarding progress
  • Help support lab organization and logistics

Ideal Qualifications:

  • Highly motivated and independent, with the ability to work in a dynamic team environment, seeking a long term position
  • Excellent organizational skills and attention to detail
  • Experience with bacterial 16S rRNA gene sequencing strongly preferred
  • Strong oral and written communication skills
  • Laboratory experience required
  • Flexibility to occasionally work evenings or weekends
  • Experience with next generation sequencing, cell culture strongly preferred
  • Computer experience including expertise with Microsoft Office programs is essential
  • Experience with R is preferred but not essential

Application information:

Please send your resume, cover letter, and contact information for three references to Dr. Doug Kwon (dkwon@mgh.harvard.edu). Unfortunately, due to the number of applications we receive, we may not be able to reply individually to all inquiries.

Administrative Assistant

Direct Supervisor:  Blythe Gulley, Project Manager
Email: bbgulley@mgh.harvard.edu
Phone: (857) 268-7160
Website: www.kwonlab.org

Employing Hospital and Department: Ragon Institute of MGH, MIT, and Harvard
Minimum degree and field of knowledge: Bachelor’s degree required
Years experience required: 0-2 years of work

Summary:

This position is located at the Ragon Institute in Cambridge, MA and is a part of Massachusetts General Hospital, MIT, and Harvard Medical School. We are a results-oriented group of highly motivated scientists from the fields of immunology, virology, genetics, vaccinology, and technology development who perform translational research to treat and prevent HIV. At every level, we value intelligence, teamwork, dedication and creativity, and we’re always looking for people with those skills who thrive in teams and dynamic environments. We are passionate about understanding the relationship between immune responses and HIV in mucosal surfaces within the context of global health and women’s health research!

Reporting to Dr. Douglas Kwon (www.kwonlab.org) and Dr. Shiv Pillai, the Staff Assistant provides administrative support and serves as a point of contact for PIs in a professional, courteous, and helpful manner. The role also includes occasionally serving as project assistant for the planning of educational workshops taught by Dr. Kwon.

 

We’re looking for a someone who is eager to grow in this role, eventually taking on additional responsibility and visibility within the Kwon and Pillai Labs.

This role is open to a hybrid model: three (3) days in-person, two (2) days remote at the Ragon Institute in Cambridge, MA.

Job Duties: 

  • Administrative support for senior faculty members, including calendar management, scheduling meetings and teleconferences, and arranging domestic/international travel
  • Assorted administrative tasks and miscellaneous errands as needed
  • Process expense reports, invoices, vendor check requests, and advanced authorization requests for special events
  • Assist with prospective applicant onboarding and new-hire support
  • Work with project manager staff to ensure compliance with research regulatory matters
  • Act as liaison between PI, lab personnel, and Ragon administrators
  • Manage the lab website and social media

Ideal Qualifications:

  • Excellent calendar and time management skills, and the ability to manage complex operations in a fast-paced environment
  • Executive-level interpersonal skills needed to interact with all levels of management and staff
  • Experience with event planning and scheduling travel arrangements preferred
  • Professional demeanor, proactive, resourceful and efficient in all tasks
  • Occasional evening and weekend work related to special events and meetings may be required
  •  

Additional Qualifications:

Must possess superior organizational and communication skills. Candidate must be able to take initiative, to work independently and as part of a team, to prioritize tasks and complete assignments with accuracy. Should have strong written and oral communication skills and be capable of preparing draft correspondence. Potential for growth in this position is a must.

 

Application information: The position is open immediately although the start date is flexible. Please submit a cover letter, CV, and references to Blythe Gulley (Project Manager) at bbgulley@mgh.harvard.edu.